A simple, sensitive and specific UV spectrophotometric method was developed for the estimation of MFNC in tablet dosage form. According to Indian pharmacopoeia and British pharmacopoeia MFNC freely soluble in 0.1 M NaOH. So UV spectrophotometric estimation was done in 0.1 M NaOH as solvent. The optimum conditions for the analysis of the drug were established. The wavelength maxima (λ max) for Mefenamic acid were found to be 285 nm in 0.1 M NaOH. Beer’s law was obeyed in the concentration range of 5‐30 µg/ml. The slope, intercept, correlation coefficient, detection and quantization limits were also calculated. The proposed method has been applied successfully for the analysis of the drug in pure and in its tablets dosage forms.
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